Iridium in PDB 2b0u: The Structure of the Follistatin:Activin Complex

The structure of The Structure of the Follistatin:Activin Complex, PDB code: 2b0u was solved by T.B.Thompson, T.F.Lerch, R.W.Cook, T.K.Woodruff, T.S.Jardetzky, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.35 / 2.80
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	109.250, 120.820, 70.570, 90.00, 90.00, 90.00
R / Rfree (%)	26.5 / 29.7

The binding sites of Iridium atom in the The Structure of the Follistatin:Activin Complex (pdb code 2b0u). This binding sites where shown within 5.0 Angstroms radius around Iridium atom.
In total 5 binding sites of Iridium where determined in the The Structure of the Follistatin:Activin Complex, PDB code: 2b0u:
Jump to Iridium binding site number: 1; 2; 3; 4; 5;

Iridium binding site 1 out of 5 in the The Structure of the Follistatin:Activin Complex


Mono view


Stereo pair view

A full contact list of Iridium with other atoms in the Ir binding site number 1 of The Structure of the Follistatin:Activin Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ir504 b:70.4 occ:0.10 OE2 A:GLU3 4.1 0.7 1.0 NZ A:LYS13 4.4 68.0 1.0 CE A:LYS13 4.5 67.9 1.0 ND2 A:ASN38 4.7 63.0 1.0 CD A:LYS13 4.9 66.6 1.0 CG A:GLU3 5.0 97.5 1.0

Iridium binding site 2 out of 5 in the The Structure of the Follistatin:Activin Complex


Mono view


Stereo pair view

A full contact list of Iridium with other atoms in the Ir binding site number 2 of The Structure of the Follistatin:Activin Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ir502 b:79.7 occ:0.25 O B:HOH518 2.9 65.5 1.0 CD B:GLN15 3.4 92.9 1.0 CG B:GLN15 3.4 89.1 1.0 NE2 B:GLN15 3.5 96.0 1.0 OE1 B:GLN15 4.0 94.4 1.0 ND2 B:ASN38 4.2 60.1 1.0 OD1 B:ASN38 4.3 59.1 1.0 CG B:ASN38 4.6 59.3 1.0 CB B:HIS36 4.6 55.5 1.0 CB B:GLN15 4.8 83.2 1.0 CG B:HIS36 5.0 59.4 1.0

Iridium binding site 3 out of 5 in the The Structure of the Follistatin:Activin Complex


Mono view


Stereo pair view

A full contact list of Iridium with other atoms in the Ir binding site number 3 of The Structure of the Follistatin:Activin Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Ir503 b:94.6 occ:0.25 OG C:SER284 4.6 91.9 1.0

Iridium binding site 4 out of 5 in the The Structure of the Follistatin:Activin Complex


Mono view


Stereo pair view

A full contact list of Iridium with other atoms in the Ir binding site number 4 of The Structure of the Follistatin:Activin Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Ir505 b:97.9 occ:0.10 NZ C:LYS48 2.4 73.0 1.0 O D:HOH528 2.6 66.2 1.0 O D:HOH505 3.4 59.7 1.0 CE C:LYS48 3.9 74.2 1.0 NH2 D:ARG192 4.6 73.4 1.0 CD C:LYS48 4.9 72.8 1.0

Iridium binding site 5 out of 5 in the The Structure of the Follistatin:Activin Complex


Mono view


Stereo pair view

A full contact list of Iridium with other atoms in the Ir binding site number 5 of The Structure of the Follistatin:Activin Complex within 5.0Å range:

T.B.Thompson, T.F.Lerch, R.W.Cook, T.K.Woodruff, T.S.Jardetzky. The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding. Dev.Cell V. 9 535 2005.
ISSN: ISSN 1534-5807
PubMed: 16198295
DOI: 10.1016/J.DEVCEL.2005.09.008